If you're going to Ybor, stay on (or very close to 7th) in the daylight or bring a weapon so you can at least return fire.
Ybor is surrounded by bad neighborhoods and industrial areas and has a liquor based joint every 2 feet. It makes for a great melting pot of thugs, the homeless and 21 year old, liquored up frat boys.
That being said, King Corona is pretty cool and there are a few cigar storefronts. There are a lot of decent B&Ms and cigar bars all around the Tampa Bay area, so which place has a lot to do with where you are staying.